Clinical Trial Brings CAR T-cell Therapy to Lupus Treatment
Providence St. Jude is among a handful of hospitals participating in a Phase 1 clinical trial for an allogeneic off-the-shelf CAR T-cell therapy for moderate-to-severe systemic lupus erythematosus. Preclinical trial results have been remarkable, demonstrating a rapid, deep, and sustained elimination of autoreactive cells, allowing some patients to eliminate their use of immune-suppressant drugs.
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