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Clinical Trial Brings CAR T-cell Therapy to Lupus Treatment

Providence St. Jude is among a handful of hospitals participating in a Phase 1 clinical trial for an allogeneic off-the-shelf CAR T-cell therapy for moderate-to-severe systemic lupus erythematosus. Preclinical trial results have been remarkable, demonstrating a rapid, deep, and sustained elimination of autoreactive cells, allowing some patients to eliminate their use of immune-suppressant drugs.

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abstract illustrated representation of a liver

First Noninvasive Treatment for Liver Cancer

Histotripsy, a highly effective noninvasive treatment for primary and metastatic liver tumors, is being used at Providence St. Jude to precisely “liquify” tumors in a single procedure—no incision or hospital stay needed.

One of just two dozen hospitals in the nation offering the recently FDA-approved technology, robotic-assisted histotripsy uses high-energy ultrasound waves to create micro-bubbles that rapidly expand and collapse inside the tumor, causing the cancer cells to break apart.

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doctor in mask and glasses for robotic surgery

Top Hospital for Surgical Excellence

We have again been named one of America’s 50 Best Hospitals in Surgical Excellence by Healthgrades. The ranking recognizes hospitals with top clinical outcomes across 15 of the most common hospital surgical procedures including cardiac, vascular, joint replacement, prostate, spine, and gastrointestinal surgeries.

brain image showing nerve pathways

A Rare Condition, a Restored Life

For individuals with trigeminal neuralgia, there are no polite adjectives for the pain: “excruciating,” “unbearable” and “the worst pain imaginable” are common. Medical journals refer to as the most agonizing condition a person can experience.

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Meet Our Physicians

headshot of Dr. Sandhya John

Sandhya M. John, MD

Pathology

Sandhya.John@stjoe.org
headshot of Dr. Shirley Pang

Shirley Pang, MD

Rheumatology

Shirley.Pang@stjoe.org
headshot of Dr. Erick Westbroek

Erick Westbroek, MD

Neurosurgery, Spine Surgery

Erick.Westbroek@stjoe.org